cefotetan disodium /sē′fōtet″ən/ , a parenteral second-generation cephalosporin antibiotic with greater activity against anaerobes and gram-negative bacilli than first-generation cephalosporins. ▪ INDICATIONS: It is prescribed for bacterial infections of the lower respiratory tract, urinary tract, skin, abdomen, bones or joints, or reproductive organs and for surgical prophylaxis. ▪ CONTRAINDICATIONS: It is contraindicated for patients who are hypersensitive to cefotetan or to other cephalosporin antibiotics. ▪ ADVERSE EFFECTS: Among adverse reactions reported are skin rash, diarrhea, eosinophilia, positive Coombs’ test results, and elevated liver enzyme levels.
