cefazolin sodium /sēfaz″ōlin/ , a cephalosporin antibiotic. ▪ INDICATIONS: It is prescribed in the treatment of infections caused by susceptible bacterial strains. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to any cephalosporin medication prohibits its use, as does severely impaired renal function. It is used with caution in patients who are allergic to penicillin or other drugs. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are pain at the site of injection and hypersensitivity reactions.