cardiac radionuclide imaging [Gk, kardia + L, radiare, to shine, nucleus, nut kernel, imago, image] , the noninvasive examination of the heart, using a radiopharmaceutical and a detection device, such as a gamma camera, positron camera, or rectilinear scanner. Clinical applications of cardiac radionuclide imaging are the gated cardiac blood pool scan, myocardial imaging, and detection of myocardial necrosis.