carbamide peroxide /kär″bəmīd/ , a topical antiinfective. ▪ INDICATIONS: It is prescribed to treat canker sores and other minor inflammatory conditions of the gums and mouth and to soften impacted earwax. ▪ CONTRAINDICATIONS: Perforated eardrum prohibits its use. ▪ ADVERSE EFFECTS: The most serious adverse reaction is local irritation.