captopril /kap″tōpril/ , an angiotensin-converting enzyme inhibitor. ▪ INDICATIONS: It is prescribed for the treatment of hypertension and congestive heart failure. ▪ CONTRAINDICATIONS: Known sensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are hypotension, proteinuria, renal failure, neutropenia, agranulocytosis, angioneurotic edema, angina, myocardial infarction, Raynaud’s disease, cough, hyperkalemia, and congestive heart failure.