capecitabine, an antineoplastic and antimetabolite. ▪ INDICATIONS: It is used to treat metastatic colorectal and breast cancers. ▪ CONTRAINDICATIONS: Pregnancy and known hypersensitivity to 5-fluorouracil prohibit its use. It also should not be used in infants. ▪ ADVERSE EFFECTS: Life-threatening effects include neutropenia, lymphopenia, thrombocytopenia, and myelosuppression. Other serious adverse effects include anemia, hyperbilirubinemia, and edema. Common side effects include nausea, vomiting, anorexia, diarrhea, and stomatitis.
