butyrophenone /byo̅o̅′tərōfē″nōn/ , one of a group of structurally related antipsychotics. They are used in treating psychosis, to decrease the choreic symptoms of Huntington’s disease and the tics and coprolalia of Gilles de la Tourette’s syndrome, and are used as an adjunct in neuroleptanesthesia. Principal butyrophenones are haloperidol and droperidol. Butyrophenones are pharmacologically and clinically similar to phenothiazines.
