blue baby [OFr, blou + ME, babe] , (Informal) an infant born with cyanosis caused by a congenital heart lesion that results in a right-to-left shunt, most commonly tetralogy of Fallot. Other causative lesions include transposition of the great vessels, and incomplete expansion of the lungs (congenital atelectasis). Congenital cyanotic heart lesions are diagnosed by cardiac catheterization, angiography, or echocardiography and are corrected surgically, preferably in early childhood. See also congenital cardiac anomaly, tetralogy of Fallot, transposition of the great vessels.