blocking [ME, blok] , 1. preventing the transmission of an impulse, such as by an antiadrenergic agent or by the injection of an anesthetic. 2. interrupting an intracellular biosynthetic process, such as by the injection of actinomycin D or the action of an antivitamin. 3. an interruption in the spontaneous flow of speech or thought. 4. repressing an idea or emotion to prevent it from obtruding into the consciousness.