benzthiazide /benzthī″əzid/ , a diuretic and antihypertensive. ▪ INDICATIONS: It is prescribed in the treatment of hypertension and edema. ▪ CONTRAINDICATIONS: Anuria or known hypersensitivity to this drug, to other thiazide medication, or to sulfonamide derivatives prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypokalemia, hyperglycemia, hyperuricemia, and hypersensitivity reactions.