aurothioglucose /ôr′ōthī′ōglo̅o̅″kōs/ , an organic gold compound used as a disease-modifying antirheumatoid drug. ▪ INDICATIONS: It is prescribed for adjunctive treatment of adult and juvenile rheumatoid arthritis, but generally no longer considered first-line therapy. ▪ CONTRAINDICATIONS: Severe uncontrolled diabetes, renal or hepatic dysfunction, a history of infectious hepatitis, hypertension, heart failure, systemic lupus erythematosus, agranulocytosis, hemorrhagic diathesis, pregnancy, urticaria, eczema, colitis, or known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are kidney and liver damage and allergic reactions. Dermatitis and lesions of mucous membranes are common.
