atropine sulfate poisoning [Gk, Atropos, fate; L, sulphur + potio, drink] , toxic effects of an overdose of a drug sometimes used as an adjunct to general anesthesia and to treat bradycardia. Symptoms include tachycardia, hot and dry flushed skin, dry mouth with thirst, restlessness and excitement, urinary retention, constipation, and a burning pain in the throat.