Aran-Duchenne muscular atrophy

Aran-Duchenne muscular atrophy /aran″do̅o̅shen″/ [François A. Aran, French physician, 1817–1861; Guillaume B.A. Duchenne, French neurologist, 1806–1875] , a form of amyotrophic lateral sclerosis affecting the hands, arms, shoulders, and legs at the onset before becoming more generalized.