Apert’s syndrome /äperz″/ [Eugène Charles Apert, French pediatrician, 1868–1940] , a rare genetic condition characterized by an abnormal craniofacial appearance in combination with partial or complete fusion (webbing) of the fingers and toes. Also called acrocephalosyndactyly. Should not be confused with Alport’s syndrome. ▪ OBSERVATIONS: Signs of Apert’s syndrome include a peaked and vertically elongated head, widespread and bulging eyes, and a high, arched posterior palate with bony defects of the maxilla and the mandible, including cleft palate or uvula and extreme malocclusion. The degree of fusion varies greatly and may be complete. ▪ INTERVENTIONS: There is no known cure for Alpert’s syndrome. Surgery to correct abnormalities may be performed. ▪ PATIENT CARE CONSIDERATIONS: A characteristic feature is the premature joining of cranial bones, with resultant growth disturbances.
