antihemophilic factor VII concentrate (AHF) /-hē′mōfil″ik/ , plasma derivative used to treat bleeding in hemophilia A patients. May be prepared by fractionation of human plasma or affinity column purification. A recombinant DNA product is also available. ▪ CONTRAINDICATIONS: There are no known contraindications. ▪ ADVERSE EFFECTS: The most serious adverse reaction is hepatitis, which occurs because the factor is obtained from pools of human plasma. Allergic reactions may also occur.
