angiokeratoma corporis diffusum, a rare familial disease in which glycolipids are stored in many parts of the body, especially in the venous and cardiovascular systems, causing vasomotor, urinary, and cutaneous disorders and in some cases, muscular abnormalities. Characteristic signs are dilation of blood vessels in the bathing suit areas; edema; hypertension; cardiomegaly, especially enlargement of the left ventricle; diffuse nodularity of the skin; albumin, erythrocytes, leukocytes, and casts in the urine; and vacuoles in muscle bundles. Also called diffuse angiokeratoma, Fabry’s syndrome, Fabry’s disease.
