Angelman’s syndrome /ān′jəl·mənz/ , [Harry Angelman, English physician, 1915–1996], an autosomal-recessive syndrome characterized by jerky puppetlike movements, frequent laughter, cognitive impairment and delayed motor development, a peculiar open-mouthed facial expression, and seizures. It can be caused by a deletion on chromosome 15 inherited from the mother; the same deletion inherited from the father causes Prader-Willi syndrome.
