amphotericin B /am′fəter″əsin/ , an antifungal medication. ▪ INDICATIONS: It is prescribed for topical or systemic use in the treatment of fungal infections. ▪ CONTRAINDICATIONS: Known hypersensitivity prohibits its use. ▪ ADVERSE EFFECTS: When it is used systemically, among the most serious adverse reactions are anaphylaxis, thrombophlebitis, blood dyscrasia, nephrotoxicity, nausea, and fever; chills and shaking may occur on administration. With topical use, local hypersensitivity reactions are the most common adverse reactions.
