amoxapine /əmok″sepin/ , a tetracylic antidepressant (sometimes classified as a secondary amine tricylic). ▪ INDICATIONS: It is prescribed in the treatment of mental depression. ▪ CONTRAINDICATIONS: It is used with caution in conditions in which anticholinergics are contraindicated, in seizure disorders, and in cardiovascular disorders. Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are sedation and anticholinergic side effects. A variety of GI, cardiovascular, and neurological reactions may also occur. It is involved in many drug interactions.
