amitriptyline /am′itrip″tilin/ , a tricyclic antidepressant. ▪ INDICATIONS: It is prescribed in the treatment of depression and has unlabeled uses for treating neuropathic pain and headaches. ▪ CONTRAINDICATIONS: Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, or known hypersensitivity to this drug or to other tricyclic medications prohibits its use. It is used with caution in patients who have a seizure disorder or cardiovascular disease or who are at risk for suicide. ▪ ADVERSE EFFECTS: Among the more common adverse reactions are sedation and anticholinergic effects. A variety of cardiovascular and central nervous system effects may occur. This agent interacts with many other drugs.
