algodystrophy /al′gōdis″trəfē/ , a painful wasting of the muscles of the hands, often accompanied by tenderness and a loss of bone calcium. The condition may begin in the hand or in the shoulder and spread over the entire limb, causing contractures, edema, and cyanosis of the skin. It may also occur in the feet or legs. It may be associated with injury, heart disease, stroke, or a viral infection. Also called complex regional pain syndrome. See also reflex sympathetic dystrophy.