alendronate, a bone-resorption inhibitor. ▪ INDICATIONS: This drug is used to treat osteoporosis in postmenopausal women and Paget’s disease. ▪ CONTRAINDICATIONS: Known hypersensitivity to biphosphonates prohibits the use of this drug. ▪ ADVERSE EFFECTS: Side effects include anemia, hypokalemia, hypomagnesemia, hypophosphatemia, osteonecrosis of the jaw, abdominal pain, anorexia, constipation, nausea, vomiting, bone pain, hypertension, urinary tract infection, and fluid overload.
