Albright’s syndrome

Albright’s syndrome /ôl″brīts/ [Fuller Albright, American physician and endocrinologist, 1900–1969] , a disorder characterized by fibrous dysplasia of bone, isolated brown macules on the skin, and endocrine dysfunction. It causes precocious puberty in girls but not in boys. The bone lesions are reddish gray, gritty fibromas containing areas of coarse fiber that may be confined to one bone or that occur in several areas, frequently causing deformities, pain, and pathological fractures. Treatment may involve osteotomy, curettage, and bone grafts. Also called McCune-Albright syndrome.

Albright’s syndrome (Courtesy Dr. David Atherton)