acebutolol /as′əbo̅o̅″təlol/ , an antiadrenergic agent that inhibits the stimulation of the central nervous system alpha-adrenergic receptors and decreases sympathetic stimulation to the blood vessels and the heart. ▪ INDICATIONS: It is prescribed in the treatment of hypertension, angina pectoris, ventricular arrhythmias, and other cardiovascular disorders. ▪ CONTRAINDICATIONS: The drug should not be given to patients with asthma, persistent severe bradycardia, second- and third-degree heart block, overt heart failure, cardiogenic shock, and peripheral vascular disease. It is generally not recommended during pregnancy. ▪ ADVERSE EFFECTS: The most common side effects include fatigue, bradycardia, bronchospasm, flatulence, hypotension, muscle and joint pains, nausea, constipation, diarrhea, headache, rash, dizziness, and insomnia.
