coupling /kup″ling/ [L, copula, bonding] , 1. the act of coming together, joining, or pairing. 2. (in genetics) the situation in linked inheritance in which the nonalleles of two or more mutant genes are located on the same chromosome and are close enough that they are likely to be inherited together. 3. (in radiation therapy) the efficiency of transfer of power from an applicator to the treatment site. Compare repulsion. See also cis configuration. 4. (in cardiology) the regular occurrence of a premature beat.
