Conradi-Hünermann syndrome /kon·rä′dē· hu′nər·män/ [Erich Conradi, German physician, 20th century; Carl Hünermann, German physician, 20th century] , a rare genetic disorder characterized by skeletal malformations, skin abnormalities, cataracts, and short stature. The specific symptoms and severity of the disorder may vary greatly from one individual to another. Conradi-Hünermann syndrome is classified as a form of chondrodysplasia punctata, a group of disorders characterized by the formation of small, hardened spots of calcium on the “growing portion” or heads of the long bones (stippled epiphyses) or inside other areas of cartilage in the body. Conradi-Hünermann syndrome is inherited as an X-linked dominant trait that occurs almost exclusively in females.
