coagulation /kō·ag′yəlā″shən/ [L, coagulare, to curdle] , 1. the process of transforming a liquid into a solid, especially of the blood. See also blood clotting. 2. (in colloid chemistry) the transforming of the liquid dispersion medium into a gelatinous mass. 3. the hardening of tissue by some physical means, as by electrocoagulation or photocoagulation. −coagulable, adj.