clopidogrel, a platelet aggregation inhibitor. ▪ INDICATIONS: It is used to reduce the risk of stroke and myocardial infarction in high-risk patients. ▪ CONTRAINDICATIONS: Known hypersensitivity, active bleeding, and increased risk for bleeding (e.g., peptic ulcers) prohibits its use. ▪ ADVERSE EFFECTS: Intracranial hemorrhage is a potential life-threatening side effect. Other adverse effects include rash, pruritus, nausea, vomiting, diarrhea, epistaxis, purpura, edema, hypertension, chest pain, headache, dizziness, musculoskeletal pain, upper respiratory tract infection, bronchitis, urinary tract infection, and hypercholesterolemia.