clobetasol propionate /klōbet″əsol prō″pyōnāt/ , a topical corticosteroid antiinflammatory. ▪ INDICATIONS: It is prescribed for the short-term treatment of inflammation and pruritus associated with certain moderate to severe types of dermatitis. ▪ CONTRAINDICATIONS: It is contraindicated for prolonged use, for applications to large areas of poor skin integrity, and with the use of occlusive dressing. ▪ ADVERSE EFFECTS: Adverse reactions may include hyperglycemia, glycosuria, Cushing’s syndrome, and suppression of hypothalamic-pituitary-adrenal functions. Because of the greater ratio of skin surface to body weight in children, they are at risk of absorbing a greater proportion of topical steroid.
