cinacalcet, a calcium receptor agonist that directly lowers parathyroid hormone levels by increasing sensitivity of calcium-sensing receptors to extracellular calcium. ▪ INDICATIONS: This drug is used to treat hypercalcemia in parathyroid carcinoma and secondary hyperparathyroidism in chronic kidney disease requiring dialysis. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include dizziness, hypertension, nausea, diarrhea, vomiting, anorexia, access infection, noncardiac chest pain, asthenia, and myalgia.
