cholestyramine resin, an ion-exchange resin and antihyperlipemic agent. ▪ INDICATIONS: It is prescribed for oral administration to increase bile acid excretion in the stool, for the treatment of hyperlipoproteinemia, and for pruritus resulting from partial biliary obstruction. ▪ CONTRAINDICATIONS: Complete biliary obstruction or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are fecal impaction, GI disturbances, and depletion of vitamins A, D, and K. Constipation is common. It interferes with the absorption of many other drugs, so other medicines should be given 1 hr before or 4-6 hr after cholestyramine.
