cetylpyridinium chloride /sē′təlpī′ridin″ē·əm/ , an antiinfective used as a preservative in pharmaceutic preparations and as a topical cleanser and local anesthetic (Cepacol). It is inactivated by soap, serum, and tissue fluids; therefore, the surface of the skin must be clean and well rinsed. ▪ INDICATIONS: It is prescribed prophylactically to prevent infection of the skin or mucous membranes. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug is the only contraindication.