cephapirin /sef″əprin/ , a parenteral first-generation cephalosporin antibiotic. ▪ INDICATIONS: It is prescribed in the treatment of bacterial infections caused by cephapirin-susceptible strains of a wide variety of microorganisms that cause septicemia, endocarditis, osteomyelitis, and bacterial infections of the respiratory tract, urinary tract, and skin. ▪ CONTRAINDICATIONS: Known sensitivity to cephalosporin antibiotics prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are neutropenia, leukopenia, anemia, bone marrow depression, and allergic reactions.
