cefuroxime sodium /sef′o̅o̅rok′zēm/ , a cephalosporin antibiotic. ▪ INDICATIONS: It is prescribed in the treatment of lower respiratory tract, urinary tract, skin, and gonococcal infections; bacterial septicemia; and meningitis and for the prevention of postoperative infections. ▪ CONTRAINDICATIONS: Hypersensitivity to the cephalosporins or known sensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are pruritus, urticaria, transient eosinophilia, neutropenia, leukopenia, and injection site reactions.