Camurati-Engelmann disease [Mario Camurati, Italian physician, 1896–1948; Guido Engelmann, 20th-century Czechoslovakian surgeon] , an inherited disorder of bone development marked by an onset of symptoms of muscular pain, weakness, and wasting, mainly in the legs, during childhood. The symptoms vary individually from mild to disabling. Radiographic examination usually reveals thickening of the periosteal and medullary surfaces of the diaphyseal edges of the long bones. In some cases compression of nerve tissue may occur. The symptoms usually subside during early adulthood. Also called progressive diaphyseal dysplasia.