calcification [L, calx + facere, to make] , the accumulation of calcium salts in tissues. Normally, about 99% of all the calcium entering the human body is deposited in the bones and teeth; the remaining 1% is dissolved in body fluids such as blood. Disorders affecting the delicate balance between calcium and other minerals, parathyroid hormone, and vitamin D can result in calcium deposits in arteries, kidneys, lung alveoli, and other tissues, interfering with normal organ function. See also calcitonin, calcium, calculus.