bexarotene, a second-generation retinoid. ▪ INDICATIONS: This drug is prescribed for cutaneous T cell lymphoma. Investigational uses include treatment of breast cancer. ▪ CONTRAINDICATIONS: Pregnancy and known hypersensitivity to retinoids prohibit bexarotene’s use. ▪ ADVERSE EFFECTS: Life-threatening adverse reactions include acute pancreatitis, leukopenia, and neutropenia. Other serious side effects include asthenia, infection, anemia, and hypothyroidism. Among the drug’s common side effects are headache, nausea, abdominal pain, and diarrhea.
