betaxolol hydrochloride /betak″səlol/ , a topical drug for open-angle glaucoma (Betoptic). An oral preparation (Kerlone) is indicated for the management of hypertension. ▪ INDICATIONS: It is prescribed for the relief of ocular hypertension and chronic open-angle glaucoma (ophthalmic) and for the management of hypertension (oral). ▪ CONTRAINDICATIONS: Betaxolol hydrochloride is contraindicated in patients with sinus bradycardia, greater than first-degree atrioventricular (AV) block, cardiogenic shock, and overt heart failure. The ophthalmic preparation is used with caution by patients who are also receiving oral beta-adrenergic blocking drugs. ▪ ADVERSE EFFECTS: Adverse reactions include stinging and tearing of the eyes. Systemic effects are rare. Adverse effects of the oral preparation are bradycardia, fatigue, dyspnea, and lethargy.
