benzodiazepine derivative /ben′zōdī·az″əpin/ , one of a group of psychotropic agents, including the tranquilizers chlordiazepoxide, diazepam, oxazepam, lorazepam, and chlorazepate, prescribed to alleviate anxiety, and the hypnotics flurazepam and triazolam, prescribed in the treatment of insomnia. Tolerance and physical dependence occur with prolonged high dosage. Withdrawal symptoms, including seizures, may follow abrupt discontinuation. Adverse reactions to the benzodiazepines include drowsiness, ataxia, and a paradoxic increase in aggression and hostility. These reactions are not common with the usual recommended dosage.
