Behçet’s disease /bā″sets/ [Hulusi Behçet, Turkish dermatologist, 1889–1948] , a rare syndrome that includes a severe, chronic, multisystem inflammatory illness of unknown cause. Also called Behçet’s syndrome. ▪ OBSERVATIONS: The disease mostly affects young males and is characterized by severe uveitis and retinal vasculitis. Other signs may include optic atrophy and small, shallow, painful white or gray lesions of the mouth and the genitals, indicating diffuse vasculitis. It may involve all organs and affect the central nervous system. ▪ INTERVENTIONS: Corticosteroids and immunosuppressive therapy may be considered. Treatment is symptomatic and focuses on reducing discomfort and preventing serious complications. ▪ PATIENT CARE CONSIDERATIONS: The disease is common in Japan, Turkey, and Israel, but rare in the United States. The variability of symptoms makes the coordination of care an important consideration.
