yellow fever, an acute arbovirus infection transmitted by mosquitoes. It is characterized by headache, fever, jaundice, vomiting, and bleeding. There is no specific treatment, and mortality is about 5%. Recovery is followed by lifelong immunity. Immunization for travelers to endemic areas is advised. The vaccine against yellow fever is highly effective, producing a greater-than-10-year immunity to the disease. Nonhuman primates are a reservoir of infection.