tuberculous spondylitis, a rare, grave form of tuberculosis caused by the invasion of Mycobacterium tuberculosis into the spinal vertebrae. The intervertebral disks may be destroyed, resulting in the collapse and wedging of affected vertebrae and the shortening and angulation of the spine. Thoracic vertebrae are more frequently involved than the vertebrae of the lumbar, cervical, or sacral segments of the spine. More than one area of the spine may be affected, and normal vertebrae may be evident between affected sections. The infection characteristically dissects vertebrae anterolaterally and produces abscesses. The pressure of the abscess may cause ischemic paralysis in the subjacent spinal cord, and abscesses in the cervical area may displace or obstruct the trachea and the esophagus. Treatment requires an extended regimen of at least three anti-tuberculosis drugs. Also called Pott’s disease, spinal caries. See also tuberculosis.
