trimethoprim /trīmeth″əprim/ , an antibacterial. ▪ INDICATIONS: It is prescribed in the treatment of infections, particularly of the urinary tract, middle ear, and bronchi. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or megaloblastic anemia resulting from folate deficiency prohibits its use. It should not be used to treat streptococcal pharyngitis. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are blood dyscrasias and allergic, GI, and central nervous system disorders.
