trihexyphenidyl hydrochloride /trīhex′ifen″idil/ , an anticholinergic agent. ▪ INDICATIONS: It is prescribed in the treatment of Parkinson’s disease and to control drug-induced extrapyramidal reactions. ▪ CONTRAINDICATIONS: Narrow-angle glaucoma, asthma, obstruction of the genitourinary or GI tract, severe ulcerative colitis, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are blurred vision, central nervous system effects, tachycardia, dry mouth, decreased sweating, and hypersensitivity reactions.