trientine hydrochloride /trī·en″tēn/ , an oral medication for treatment of an inherited defect in copper metabolism (Wilson’s disease). ▪ INDICATIONS: It is prescribed for the relief of symptoms of Wilson’s disease for people who cannot tolerate penicillamine. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: The most serious side effects are possible iron deficiency and hypersensitivity reactions.