treponematosis /trep′ənē′mətō″sis/ pl. treponematoses [Gk, trepein + nema + osis, condition] , any disease caused by spirochetes of the genus Treponema. All these infections are effectively treated with penicillin; often one dose, given intramuscularly, results in cure. Kinds include bejel, pinta, syphilis, yaws.