tramadol, a central analgesic. ▪ INDICATIONS: It is used to manage moderate to severe pain. ▪ CONTRAINDICATIONS: Factors that prohibit its use are known hypersensitivity to this drug or acute intoxication with any central nervous system depressant. ▪ ADVERSE EFFECTS: Seizures and GI bleeding are life-threatening effects. Other adverse effects are dizziness, central nervous system stimulation, somnolence, headache, anxiety, confusion, euphoria, hallucination, nausea, constipation, vomiting, dry mouth, diarrhea, abdominal pain, anorexia, flatulence, vasodilation, orthostatic hypotension, tachycardia, hypertension, abnormal electrocardiograms, pruritus, rash, urticaria, vesicles, urinary retention or frequency, menopausal symptoms, dysuria, and menstrual disorders.
