toxic epidermal necrolysis (TEN), a rare life-threatening skin disease characterized by epidermal erythema, superficial necrosis, and skin erosions. This condition, which affects mainly adults, makes the skin appear scalded, often leaving scars. The cause of TEN is unknown, but it may result from toxic or hypersensitive reactions, an immune response, or severe physiological stress. A similar skin disorder may be the result of a staphylococcal infection. Treatment of TEN commonly involves the administration of IV fluids to replace body fluids and maintain electrolyte balance. Frequent laboratory analyses are necessary to monitor hematocrit and hemoglobin, serum proteins, electrolytes, and blood gases. Also called scalded skin syndrome. Compare staphylococcal scalded skin syndrome.
