TOLAZamide /tolaz′əmīd/ , an oral sulfonylurea antidiabetic agent. ▪ INDICATIONS: It is prescribed in the treatment of stable or type 2 diabetes and for some patients sensitive to other types of sulfonylureas or who have failed to respond to other similar drugs. ▪ CONTRAINDICATIONS: Unstable diabetes; serious impairment of renal, hepatic, or thyroid function; pregnancy; or known hypersensitivity to this drug or other sulfonylurea medications prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypoglycemia and skin reactions. Blood dyscrasias may occur.
