tipranavir, an antiretroviral. ▪ INDICATIONS: This drug is used in combination with other antiretrovirals to treat HIV. ▪ CONTRAINDICATIONS: Hepatic disease (Child-Pugh B to C) and known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include dizziness, somnolence, fatigue, anorexia, dry mouth, nephrolithiasis, rash, pain, asthenia, and hyperlipidemia. Life-threatening side effects include hepatitis B or C, fatalities when given with ritonavir, insulin-resistant hyperglycemia, and ketoacidosis. Common side effects include headache, insomnia, diarrhea, abdominal pain, nausea, and vomiting.
